Or you could file another bug, if you can't find any similar to yours. Don't forget to add backtrace and error log.
However, I'd recommend you sticking to wine 1.4 branch unless you like to experiment and want to test all new wine builds. Wine 1.4 is current stable branch, while 1.5 is unstable. So, the name says it - it is UNSTABLE. No surprise then if your favorite application won't start after upgrade :)