You should have Wine 1.6 or later to run Roblox more properly.
How to get it running
Run "winetricks vcrun2008 winhttp wininet" in a terminal. It should run near-flawlessly now.
Information regarding OpenGL vs DirectX mode
Roblox Player and Roblox Studio both work far better with OpenGL graphics enabled. Although this may be useful, it disables game recording in the Roblox Player. Game recording is not currently supported by Roblox in OpenGL mode, so if you need this feature, it's best to leave it in Direct3D mode.
To enable OpenGL mode, open the Roblox Studio, then open the Tools menu. Under Tools, click Settings, then Rendering. A prompt will come up saying "Changing settings may make ROBLOX unstable". Click OK. Under the Rendering submenu, change the option graphicsMode from Direct3D to OpenGL. Click Close and restart the Roblox Studio.
The game should now be able to achieve about double to triple the FPS it was getting while in DirectX mode.
The following comments are owned by whoever posted them. WineHQ is not responsible for what they say.
Game works, has flaws that need attention.
by Charles Swain on Saturday July 27th 2013, 1:17
The following glitches/difficulties are seen by me running ROBLOX through Wine 1.6 on Linux (after having set it up and running 'winetricks vcrun2008 winhttp wininet' in a terminal):
- (NEEDS ATTENTION) cannot load place files in Studio, can only create them.
- Parts to characters do not render. Only hats, gear, possibly custom heads, and my head appear.
- Chat bar produces random characters sometimes and there is no shift or caps locks key functionality.
- Random flickering is sometimes produced.
- Difficult to drag the window in a desktop environment, tends to go every which way.
- 'Standard' textures and sound files come up missing or unusable, either producing checkerboard patterns or not playing at all. This affects certain GUI themes, all standard buttons, certain decals, and 'movement' sounds (list probably incomplete).
That is it for me, but that was just one night of testing.