-Use the latest version of wine. Older versions will not work.
-The drivers for your video card must be installed and hardware
acceleration must be enabled. Open a terminal and type `glxinfo`. If it
says `Direct Rendering : Yes` then it should be okay. Fully tested with Nvidia GPUs+proprietary drivers. Not sure about other GPUs / drivers.
-Run the game with the "ddragonf-linux" script to enable the game specific tweaks for wine, otherwise you will have problems.