The test results you have selected are very old and may not represent the current state of Wine.
Selected Test Results (selected in 'Test Results' table below)
Everything, but I played only several minutes.
What does not
Cursor invisible until set "Hardware cursor" to "Off" in game "Settings" > "Interface".
Impossible to use GPU physics acceleration in "Settings" > "Physics".
What was not tested
All game except prologue
To hear sounds I set "Hardware acceleration" in winecfg's Audio tab to "Emulation". No sounds at all with "Full" acceleration on my system.
Low FPS on my system (Intel QX9770, GTX280, 4GB RAM). Even mouse cursor moves with some lag.
Game starts to work without installing/overiding any libraries (PhysX was installed during game install process).
"winetricks physx" didn't make any noticable changes in game performance.