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The VST plugin works great in Ableton 8.1 and WineASIO+JACK. (This plugin method is the common way of interacting with software synthesizers like Massive.) It uses a ton of processor time. I have to have the buffer in JACK cranked up to give ~200 ms lag (a bit too slow for live performance) to prevent buffer underruns.
What does not
What was not tested
didn't try routing midi to the standalone program
'gold' rather than 'platinum' only because WineASIO installation required a couple commands for my distro (besides just apt-get/yum) and JACK doesn't automagically start itself p;