The test results you have selected are very old and may not represent the current state of Wine.
Selected Test Results (selected in 'Test Results' table below)
Install, playing of game, everything that was tested works.
What does not
What was not tested
To eliminate any existing issues, I started with a clean WINEPREFIX.
I then roughly followed the guide at
The most important part to remember is to use winetricks to install directx9 and mfc42
I also found that it is unnecessary to uncheck the option "Allow the window manager to control the windows" in winecfg.
To fix a cursor bug (both mouse clicks required for a single left click) and make the game perform better, make sure you edit the file rise2.ini and change the following values:
Thanks to Damon at http://www.damonkohler.com/ for this info