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Didn't save/load game and I didn't play all the way through, but I did go through several areas of the first Sisko mission and no problems.
I had to choose "OpenGL" upon running for the 1st time to get higher than 800x600 screen resolution. Using OpenGL, my desktop resolution of 1680x1050 was detected and used automatically (not bad for an old game). It looked a little dated, but not too bad and perfectly playable. Also, I couldn't even get this old
game to run in WindowsXP SP3, so go linux! :)
1. You may need no-cd fix for this game, please check usual sources for one
2. I had to change sample rate to 22050 for sound to work properly, please let me know if you didn't have to.
3. When you first load game and it asks you to select your graphics driver; you need to select unofficial button and then OpenGL. The game might be playable in software mode but Direct3D crashes the game as soon as the engine starts and I have no desire to get it working on that mode when GL works perfectly.