Install game, change settings, select correct resolution, start game in any difficulty. Simple, everything works.
What does not
In-game overlay doesn't allows game to run.
Just turn off in-game overlay (Go to game settings, game properties and uncheck Enable Origin In Game for Dead Space™).
What was not tested
Game runs as native. I played it on Windows 10 and there is no differense with WINE. Approximately same performance.
CPU: Intel i3 4005U (2 core, 4 threads)
GPU: Nvidia Geforce 820M (Driver 390.116)
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Current||Arch Linux x86_64||Mar 31 2019||4.4-staging||Yes||Yes||Yes||Gold||Basiani|
|Show||Debian GNU/Linux Unstable "Sid" x86_64||Mar 06 2019||4.3-staging||Yes||Yes||Yes||Gold||debianxfce|
|Show||Antergos x86_64||Jun 18 2015||1.7.45||Yes||Yes||Platinum||an anonymous user|
|Show||Ubuntu 14.04 "Trusty" amd64 (+ variants like Kubuntu)||Aug 03 2014||1.7.22||Yes||Yes||Platinum||Luis Alvarado|
|Show||Gentoo Linux x86_64||Dec 19 2013||1.6.1||Yes||No||Garbage||an anonymous user|
|Bug #||Description||Status||Resolution||Other apps affected|
|15795||Dead Space crashes with unhandled exception||CLOSED||FIXED||View|
|15874||Dead Space doesn't start||CLOSED||FIXED||View|
|21230||d3dx9_36.dll: incomplete function "D3DXGetShaderConstantTableEx"||CLOSED||FIXED||View|
|25727||Dead Space resolution issues||CLOSED||FIXED||View|
|25729||Dead Space joypad always looks up (game chooses wrong axis when DirectInput is used and more than 4 axes are present)||CLOSED||DUPLICATE||View|
|25747||Very low 2d effects quality in Dead Space on fglrx||CLOSED||NOTOURBUG||View|
|25810||Dead Space crashes while rendering "chapter complete" text if input event was emited on fglrx.||CLOSED||ABANDONED||View|
|25811||Dead Space in-game text decorations and backgrounds are missing on fglrx||CLOSED||NOTOURBUG||View|
|25812||Dead Space flames and flame-alike effects are not rendered on fglrx||CLOSED||ABANDONED||View|
Use wine-1.3.6 or revert commit f0b0c1b1dddf606177651deb45c0afd6259076aa as described in RegressionTesting wiki pageWorkarounds for known bugs:
If it crashed anyway (there will be clutch in the sound and no "Chapter complete" message will appear), run console blindly and type wineserver -k.
Switch off "Decals" in Options -> Visuals -> Advanced Settings
To navigate in menu use arrows to control selection, Enter on non-submenu option is "accept", ESC - "cancel". Or you may try to guess mouse position watching at highlights.
Play with Virtual Desktop enabled: winecfg -> Graphics -> Emulate Virtual Desktop and set size for it matching your desktop resolution. Also you probably want to disable window decorations. Enabling Virtual Desktop is commonly a good this to do, as it guaranties you, that application won't mess your current resolution up, if something would go wrong.
Disconnect your gamepad before starting a game or try joypad.txt file from comments below.