Everything from installer to game play as far as I've seen so far.
What does not
Some rendering problems and the keyboard is in-op so you can't enter your city's name.
What was not tested
I only started a small city. I did not play a long time to see if there was more graphical problems due to long play time.
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Show||Ubuntu 16.04 "Xenial" amd64 (+ variants like Kubuntu)||Mar 01 2017||2.2||Yes||Yes||Silver||Jacob Cameron|
|Show||Ubuntu 16.04 "Xenial" amd64 (+ variants like Kubuntu)||Feb 04 2017||2.0||Yes||Yes||Silver||Jacob Cameron|
|Show||Ubuntu 10.04 "Lucid" amd64 (+ variants like Kubuntu)||Oct 04 2014||1.6.2||Yes||Yes||Platinum||an anonymous user|
|Show||Ubuntu 12.10 "Quantal" amd64 (+ variants like Kubuntu)||Feb 03 2013||1.5.23||Yes||No||Garbage||an anonymous user|
|Show||Ubuntu 10.04 "Lucid" amd64 (+ variants like Kubuntu)||Jun 16 2011||1.3.21||Yes||Yes||Silver||an anonymous user|
By default, SimCity 4 only allows you to use resolutions up to 1280x1024, but it's very easy to use any resolution you want, just add this to your launcher/start script:
Replace 1920x1080 with your desired resolution.