As other people have mentioned, most things generally work.
Â The only thing that really surprised me was that Reason is capable of running as a ReWire slave to 64bit REAPER, including MIDI and multiple channels of audio.
What does not
What was not tested
Playing Reason directly via MIDI and wineasio.
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Show||Ubuntu 21.04 "Hirsute" amd64 (+ variants like Kubuntu)||May 22 2021||6.9||Yes||Yes||Yes||Silver||Aleph Diallo|
|Show||Ubuntu 20.04 "Focal" (+ variants like Kubuntu)||Dec 12 2020||5.0.3||Yes||Yes||Yes||Gold||Marcel Bonnet|
|Show||Fedora 33 x86_64||Nov 25 2020||5.21-staging||Yes||Yes||Yes||Gold||enagok225|
|Show||Linux Mint Debian x86_64||Jun 02 2020||5.9||Yes||Yes||No||Silver||John|
|Current||Arch Linux x86_64||Aug 14 2016||1.9.14||Yes||Yes||Silver||an anonymous user|