From what I can tell, everything! I need to test multiplayer (I won't bother till I've clocked the game) but I bought it for single player.
Completing the game.
What does not
Patching through Origin did not work, I had to manually delete the old files and rename the patched ones. This is origin issue though but will explain more in more info.
Buying DLC through the game/origin - had to use an origin install on a windows vm.
What was not tested
Game itself works perfectly, I didn't have to touch a setting. Now for me I installed the game off the dvd's into origin. To get the game ready to play I killed the EAProxy process (do a ps -ef and kill -9 the pid). Now at this point Origin said there was a patch available so I ran it but it would fail saying the files are in use, if you go into drive_c/program files/origin games in the prefix you'll see several files in most subdirectories with STAGED at the end of the filename. If you delete the filename that matches that without the STAGED bit at the end and rename the STAGED file to the one you just deleted you'll patch the game manually. To make sure you got them all, right click the game in origin and select repair install, if it tries to do any kind of patching you missed one (and do a find for any STAGED files). Once all that is done and repair game says everything is good, you can start playing the game!
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Show||Debian GNU/Linux 7.x "Wheezy" x86_64||Oct 26 2013||1.7.1||Yes||Yes||Gold||Daniel Rammelt|
|Show||Debian GNU/Linux Unstable "Sid" x86_64||Sep 06 2013||1.7.1||Yes||Yes||Platinum||Galym Kerimbekov|
|Show||Debian GNU/Linux 7.x "Wheezy" x86_64||Dec 04 2012||1.5.18||No||Not installable||Garbage||an anonymous user|
|Show||Ubuntu 11.10 "Oneiric" amd64 (+ variants like Kubuntu)||Jun 24 2012||1.5.7||Yes||Yes||Gold||CS Williams|
|Show||Ubuntu 12.04 "Precise" i386 (+ variants like Kubuntu)||Aug 03 2012||1.4.1||Yes||Yes||Gold||Emmett Hendrick|
If you have experienced performance degradation please deactivate dynamic shadows and antialiasing from game graphic menu. Also set proprietary driver image settings to Maximum Performance. This helps for weak graphic cards like NVIDIA Geforce 120 GT.
Please note - If your mouse/keyboard isn't working then it's most likely a rawinput issue, please upgrade your wine to at least version 1.6 since wine has had rawinput built into it for about 12 minor releases now.
If you have mouse and in-game lags, set dinput to native in winecfg - Libraries tab
In some cases sound disappeared, it can be fixed by setting dsound to native as above.
If you have poor performance in multiplayer, set winhttp to native as above.
Do not start game directly from Origin Client! It crashed anytime if you do it.
1. Firstly run Origin, login into it
2. Then run Mass Effect 3 from shortcut on the desktop (or executable file)
3. Start Multiplayer and Enjoy!