The game launches, that's about it.
What does not
The game installs through origin fine, but whether launching the game from origin directly or from a second terminal running the .exe directly, the game gets to the main menu and brings up a message to say "Origin(EA) is no longer running, Mass Effect 3 will now close". The game then proceeds to exit.
I attempted to run origin in "offline mode" to resolve this, but this did not change the result.
What was not tested
Gameplay (singleplayer, multiplayer)
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Show||Ubuntu 18.04 "Bionic" amd64 (+variants like Kubuntu)||Oct 21 2019||4.18-staging||Yes||Yes||Yes||Gold||Barney Livingston|
|Show||Ubuntu 18.04 "Bionic" amd64 (+variants like Kubuntu)||Feb 23 2019||4.2||No||Not installable||No||Garbage||Wang Xuancong|
|Show||Arch Linux x86_64||Feb 06 2019||4.0-rc4-staging||Yes||Yes||No||Platinum||Eimantas|
|Show||Manjaro Linux 18.0.0||Oct 18 2018||3.18||Yes||Yes||No||Garbage||Roque|
|Current||Linux Mint 18.3 "Sylvia" x86_64||Jun 04 2018||3.9-staging||Yes||Yes||No||Garbage||James Edmonds|