Stardew Valley

What works

• Game launches both with and without the Galaxy client
• Gameplay (15+ hours of testing)
• Graphics (windowed borderless and fullscreen have minor issues)
• Sound and music
• Multiplayer through Galaxy client

What does not

• .NET framework and XNA must be installed via Winetricks, the Galaxy client fails to install these dependencies.
• When setting the game to fullscreen, the zoom level gets messed up; certain HUD elements are misplaced, the camera is off-center, etc.
• The task bar is still visible with borderless windowed, unlike native version.

Workarounds

• Use winetricks dotnet462 xna40 before installation.
• Fullscreen issues are easily fixed by changing the zoom level.

What was not tested

• Installation without GOG Galaxy (there's no real reason to do that; if you don't want Galaxy integration you can just play the native Linux version instead).

Hardware tested

Graphics:

• GPU: AMD
• Driver: open source

Additional Comments

Works on both 32-bit and 64-bit prefix, although the Galaxy client itself seems to have trouble with 64-bit prefixes, in my experience.

Tested on Kubuntu with KDE desktop.