ChemOffice

What works

ChemDraw works smoothly in general. The following functions have been tested with success:

• Drawing and manipulating chemical structures with simple and complex stereochemistry
• Predicting NMR spectra
• Converting structures to names and vice versa
• Saving and opening .cdx files
• Saving as other graphic formats (.png, .eps, etc.)

Chem3D also works (though less smoothly). The following functions have been tested with success:

• Drawing molecules in 2D, viewing and manipulating generated 3D structures (scaling, rotating, translating, reflecting)
• Detecting stereochemistry
• Minimising energy with MM2
• Setting up, running, and viewing MM2 dynamics and adjusting temperatures and heating rates, etc.
• Calculating and viewing Extended Huckel charges and surfaces

What does not

• Searching on SciFinder fails with error -2147467259 and may cause ChemDraw to hang
• Installing GAMESS on Chem3D (so can't use any GAMESS ab initio features)
• 3D structures disappear when Chem3D workspace is out of focus, and only reappear when the workspace is back in focus

Workarounds

(Courtesy of rc454 on the test for a previous version: https://appdb.winehq.org/objec...)

Extra libraries are required to be installed via winetricks in order to get ChemDraw and Chem3D to run:

• winetricks vb6run gdiplus vcrun2010 dotnet40

The .exe installer will not work as is. Therefore, to install ChemOffice, one first needs to decompress it using, say, 7z:

• 7z x cop16.0.1.exe

then run the installation from the msi package located in Windows/PerkinElmer/ChemOffice:

• wine msiexec.exe /i PerkinElmer_ChemOffice_Professional_2016.msi

What was not tested

More advanced features not listed above

Hardware tested

Graphics:

• GPU: Nvidia
• Driver: unknown

Additional Comments