Installing works perfectly (the patch is simply a self extractor) and launching the patch copy of the game also works.
What does not
Getting past the "Patch Detected" screen. The button you need to click to close Uplink once the changes are applied is not there, and if you close Uplink using the window widget the changes aren't applied, so next time you launch the game the same thing happens again.
What was not tested
Everything after the "Patch Detected" screen
There is a native build of Uplink available
|Operating system||Test date||Wine version||Installs?||Runs?||Used|
|Show||Ubuntu 16.10 "Yakkety" amd64 (+ variants like Kubuntu)||Nov 02 2016||1.9.20||Yes||Yes||Platinum||matheus|
|Show||Ubuntu 12.04 "Precise" amd64 (+ variants like Kubuntu)||Feb 19 2013||1.5.21||Yes||Yes||Platinum||Anthony Choate|
|Show||Ubuntu 13.04 "Raring" amd64 (+ variants like Kubuntu)||Jun 24 2013||1.4.1||Yes||Yes||Bronze||an anonymous user|
|Show||Mandriva 2010.1||Nov 03 2010||1.3.5||Yes||Yes||Platinum||Maik Wagner|
|Show||Ubuntu 9.10 "Karmic" i386 (+ variants like Kubuntu)||Feb 09 2010||1.1.38||No, but has workaround||Yes||Gold||an anonymous user|